6533b826fe1ef96bd1283a8b

RESEARCH PRODUCT

Improvement of solubility and biocompatibility of MnO based nanoparticles in aqueous solutions

Laura M. SchreiberWolfgang TremelStefan A. L. WeberThomas D. SchladtFlorian D. JochumKerstin KollPatrick Theato

subject

chemistry.chemical_classificationAqueous solutionNanostructureMaterials scienceChemical engineeringchemistryBiocompatibilitySurface modifiedPEG ratioNanoparticlePolymerSolubility

description

ABSTRACTMnO nanoparticles were surface modified using two different multifunctional polymers. By introducing a PEG group, the long term stability, MRI applicability and sterile filtration could be greatly improved. Furthermore, PEGylated MnO NPs were less toxic compared to non-PEGylated NPs. The results suggest that these nanoparticles are suitable for in vivo applications.

yearjournalcountryeditionlanguage
2011-01-01MRS Proceedings
https://doi.org/10.1557/opl.2011.870