6533b826fe1ef96bd1283b3c

RESEARCH PRODUCT

Conformational study of methyl esters of some aliphaticerythro- andthreo-dichlorocarboxylic acids

Maija Pitkänen

subject

chemistry.chemical_compoundChemistryCarbon tetrachlorideDiastereomerProton NMROrganic chemistryChemical solutionGeneral Materials ScienceGeneral ChemistryNuclear magnetic resonance spectroscopyMedicinal chemistryVicinal

description

The average conformations of methyl esters of some aliphatic erythro- and threo-dichlorocarboxylic acids in dilute carbon tetrachloride solutions have been determined from the vicinal proton–proton coupling constants and 1H NMR shifts. The 13C shift differences between the erythro and threo forms are compared and discussed with regard to the differences in the average conformations.

https://doi.org/10.1002/mrc.1270220708