6533b826fe1ef96bd1283c69
RESEARCH PRODUCT
Outcomes of Donor-Recipient Gender Mismatched Lung Transplantation in the Eurotransplant Area
Roland BuhlKonrad HoetzeneckerE.a. Van De GraafV. VerplanckeChristiane KnoopErik A M VerschuurenRobin VosRogier A.s. HoekD. HoeferJ. GotliebPatrick EvrardBenoît RondeletG LauferGyörgy LangJ.m. Kwakkel Van ErpJ. M. A. SmitsGeert VerledenChristian WittRené SchrammW. Van Der Bijsubject
Pulmonary and Respiratory MedicineTransplantationmedicine.medical_specialtyLung transplantsLungbusiness.industrymedicine.medical_treatmentOrgan transplantationmedicine.anatomical_structureInternal medicineMedicineLung transplantationSurgeryCardiology and Cardiovascular MedicinebusinessMedian survivaldescription
Purpose An effect of donor-recipient gender mismatching on long-term survival outcomes following organ transplantation has been postulated but remains controversial. We aimed to investigate the influence of gender mismatches on long-term survival after lung transplantation in the Eurotransplant area. Methods In this retrospective, multicentre study in the Eurotransplant area, all lung transplants performed from DBD lungs in the period from 01.01.2000 until 31.12.2015 were included. A total of 7688 lung transplant recipients (≥ 14 years old) for long-term survival and the effect of gender mismatches (Kaplan-Meier, multivariate regression). Results More men (4079; 52 %) were transplanted compared to women (3609; 48%). Women had better survival outcomes compared to men with a median survival of 3159 days for women compared to 2396 days for men (p Conclusion Women had better survival outcomes than men but women were significantly younger when transplanted. A female donor transplanted into male had a significant worse survival and needs further elucidation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-04-01 |