6533b826fe1ef96bd1283f3c
RESEARCH PRODUCT
Lymphadenomatous carcinoma of the sublingual gland: report of a first case in an unusual localization.
Martin KunkelAndreas SchwerdtfegerTorsten HansenYong-dae KwonStefan Biesterfeldsubject
AdultMalePathologymedicine.medical_specialtyFloor of mouthSalivary glandbusiness.industrySublingual glandCancerSublingual Gland NeoplasmsAnatomymedicine.diseaseAdenolymphomaCarcinoma Adenoid CysticMetastasisParotid glandLesionmedicine.anatomical_structureTreatment OutcomeOtorhinolaryngologymedicineCarcinomaHumansmedicine.symptombusinessdescription
Background. Lymphadenomatous carcinoma of the salivary gland is a very rare tumor, which hitherto occurred exclusively in the parotid gland. This report describes a case of lymphadenomatous carcinoma of the sublingual gland, which is thought to be the first report of this special entity. Methods and Results. A 36-year-old man was seen with slowly growing mass on his right floor of mouth. Upon surgical removal, the mass was well encapsulated. Microscopic exami- nation revealed a biphasic appearance with islands of neoplas- tic epithelial cells presenting against a dense lymphoid stroma, while the epithelial compartment showed features of malig- nancy. During 30-months of close follow-up, there has not been any sign of local recurrence or metastasis. Conclusion. The clinical behavior, the age of the patient, and the sublingual localization differentiate this lesion from the seba- ceous type, favoring lymphadenomatous carcinoma as a distinct clinical entity. V
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2008-03-11 | Headneck |