6533b826fe1ef96bd12846d4
RESEARCH PRODUCT
Enantioselective alkynylation of benzo[e][1,2,3]-oxathiazine 2,2-dioxides catalysed by (R)-VAPOL-Zn complexes: synthesis of chiral propargylic cyclic sulfamidates
José R. PedroM. Carmen MuñozAlicia MonleonLode De MunckCarlos Vilasubject
PropylaminesPropanolsStereochemistryChemistryOrganic ChemistryThiazinesEnantioselective synthesisStereoisomerismPhenanthrenesCrystallography X-RayLigandsAmidesBiochemistryCatalysisZincCatàlisiPargylineAlkynylationAlkynesFISICA APLICADAPhysical and Theoretical ChemistryEnantiomerQuímica orgànicaChromatography High Pressure Liquiddescription
[EN] (R)-VAPOL-Zn(II) complexes catalysed the enantioselective addition of terminal alkynes to cyclic benzoxathiazine 2,2-dioxides, providing the corresponding chiral propargylic sulfamidates with high yields (up to 93%) and good enantiomeric excesses (up to 87%).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-01-01 |