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RESEARCH PRODUCT
Recent advances on nanomaterial based electrochemical and optical aptasensors for detection of cancer biomarkers
Ahad MokhtarzadehMaryam HejaziBehzad BaradaranMiguel De La GuardiaAli MalekiParia Pashazadeh-panahiParia Pashazadeh-panahiReza Eivazzadeh-keihansubject
Diagnostic methodsWeb of sciencebusiness.industryAptamer010401 analytical chemistryEarly detectionCancer02 engineering and technologyComputational biology021001 nanoscience & nanotechnologymedicine.disease01 natural sciences0104 chemical sciencesAnalytical ChemistryBiomarker (cell)MedicineCancer biomarkers0210 nano-technologybusinessSpectroscopydescription
Abstract Cancer is a real menace to all societies globally since it is the leading cause of premature mortality in men and women. The incidence of malignancies is enhancing as a result of plenty factors. Physically and economically concerns that occur in cancers patients cannot be neglected. However, current diagnostic methods and cure duration do not fulfill patients requirements. Therefore, it is essential to detect and diagnose cancer biomarkers as soon as possible and overcome the current burdens. Novel aptasensors is emerging as one of the most promising strategies for early recognition of cancer. Aptamers an artificial DNA or RNA sequences, possess plenty of merits such as easy production, modification of their structure, lower immunogenicity, and high affinity to target that pave the way for early detection of cancer biomarkers. This review attempts to list novel and advanced investigation progress of aptamers in biosensor platforms for diagnosing of malignancies.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-03-01 | TrAC Trends in Analytical Chemistry |