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RESEARCH PRODUCT

Le pneumocytome sclérosant : une tumeur rare et apparemment bénigne

A. ZouakGuillaume BeltramoPierre-benoit PagèsY. HassaniM. GeorgesN. AhouansouPhilippe BonniaudPhilippe BonniaudS. Ramla

subject

Pulmonary and Respiratory MedicineGynecologymedicine.medical_specialtybusiness.industryRare tumor[SDV]Life Sciences [q-bio]Sclerosing pneumocytomaBenign tumormedicine.diseaseSclerosing pneumocytoma030218 nuclear medicine & medical imagingBenign tumor[SDV] Life Sciences [q-bio]03 medical and health sciencesRare tumorLung nodules0302 clinical medicine030220 oncology & carcinogenesisSclerosing hemangiomamedicinebusiness

description

International audience; Introduction: Sclerosing pneumocytoma is a benign and rare lung tumor affecting epithelial cells. In most cases, patients are asymptomatic and the diagnosis is made on an X ray or a CT scan performed for other enquiry. Sex ratio favors women. Epidemiological studies report that middle-aged Asian women are more frequently affected. Radiological investigations find a solitary nodule or a mass with peripheric localization. When performed, histological analysis shows a tumor composed of at least two of the four following architectures: papillary, sclerosing, hemangiomatous and solid, with two types of cells that can be round or cubic cells.Cases report: We report two cases of multiple sclerosing pneumocytoma in two caucasien men. The first patient was asymptomatic, the second complain from moderate dyspnea. A wedge resection was performed in both, allowing diagnosis. Anatomopathology revealed respectively a predominant sclerosing and solid architecture and a sclerosing and papillary architecture. There was no progression of the other concomitant nodules after three years follow-up.Conclusion: Pneumocytoma is a benign, slow-growing tumor with good prognosis.

10.1016/j.rmr.2020.08.003https://hal.archives-ouvertes.fr/hal-03492782