6533b826fe1ef96bd128519a

RESEARCH PRODUCT

Exosomes as delivery vehicles: a commentary on "Amoxicillin haptenates intracellular proteins that can be transported in exosomes to target cells".

Stefania Raimondo

subject

030213 general clinical medicineCell typeVesicleEndocytic cyclemacromolecular substancesGeneral Medicine030204 cardiovascular system & hematologyBiologyMicrovesiclesCell biology03 medical and health sciencesExosomes amoxicillin protein hapten0302 clinical medicinemicroRNAExtracellularMultivesicular BodyIntracellular

description

Exosomes are lipoproteic nanosize vesicles of endocytic origin that are released in the extracellular space by several cell types when a multivesicular body fuses with the plasma membrane (1). To date, accumulating evidences highlight the potential of exosomes as messenger in intercellular communication. Indeed, several studies reported the presence of lipids, proteins, metabolites and nucleic acid (DNA, mRNA, microRNA, lncRNA) in exosomes and highlight their functional role in physiological and pathological processes (2).

10.21037/atm.2017.01.55https://pubmed.ncbi.nlm.nih.gov/27319758