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RESEARCH PRODUCT

Granulomatous mycosis fungoides, a rare subtype of cutaneous T-cell lymphoma

Mindaugas AndrulisMarta KogutEva HadaschikStephan GrabbeAlexander EnkWolfgang Hartschuh

subject

GMF granulomatous mycosis fungoidesPathologymedicine.medical_specialtyMycosis fungoidesgranulomatous mycosis fungoidesbusiness.industryCutaneous T-cell lymphomaT-Cell Receptor Gamma GeneCase ReportDermatologyGranulomatous mycosis fungoidesmedicine.diseaseDermatologyINF-α interferon alfaGranulomatous dermatitisTCR T-cell receptormedicineT-cell receptor gamma geneMF mycosis fungoidesGranulomatous Dermatitisbusiness

description

Granulomatous mycosis fungoides (GMF) is an unusual histologic subtype of cutaneous T-cell lymphoma.1 The diagnosis of GMF is usually established after observation of a granulomatous inflammatory reaction associated with a malignant lymphoid infiltrate. Epidermotropism, a clue to diagnosis in classical mycosis fungoides (MF) may be absent in about 47% of cases of GMF.2 In some instances, the granulomatous component may be intense and obscures the lymphomatous component of the infiltrate.1 There are no distinctive clinical patterns associated with GMF.1, 3

10.1016/j.jdcr.2015.05.010http://europepmc.org/articles/PMC4809220