6533b827fe1ef96bd1285a32

RESEARCH PRODUCT

Papel de la antitrombina iii en cirugía cardiaca

V. MuedraDomingo BarettinoPilar D'ocon

subject

medicine.medical_specialtymedicine.drug_classbusiness.industryAnticoagulantAntithrombinCritical Care and Intensive Care MedicineCardiac surgeryAnesthesiology and Pain MedicineCoagulationInternal medicinemedicineCardiologyProtein activitybusinessmedicine.drug

description

Coagulation of blood is of multidisciplinary interest. Cardiac surgery produces major changes in the delicate balance between pro-and anti-coagulant serum factors. The role of antithrombin iii has been analysed after finding evidence that associated decreased levels of protein activity to postoperative morbidity and mortality. Supplementing exogenous antithrombin is considered with the aim of optimising outcomes. Its intrinsic anticoagulant and anti-inflammatory properties have stimulated a growing interest, and suggests new lines of research.

https://doi.org/10.1016/j.redar.2012.09.025