6533b827fe1ef96bd1285ad5
RESEARCH PRODUCT
Genetic data of 10 X-STRs in a Spanish population sample
M. GisbertPaula Sánchez-dizAngel CarracedoAntónio AmorimIva GomesIva GomesM. AlerLeonor Gusmãosubject
Chromosomes Human Xeducation.field_of_studyPopulationPopulation geneticsGenetic dataLocus (genetics)BiologyDNA FingerprintingPolymerase Chain ReactionhumanitiesPathology and Forensic MedicineSpanish populationExact testGenetics PopulationGene FrequencySpainTandem Repeat SequencesEvolutionary biologyHumansMicrosatelliteFemaleeducationLawAllele frequencyDemographydescription
In this work, we present population genetic data of 10 X-chromosome STRs (DXS8378, DXS9898, DXS8377, HPRTB, GATA172D05, DXS7423, DXS6809, DXS7132, DXS101 and DXS6789) obtained from sample of 145 unrelated female individuals belonging to Valencia (Spain), a region located in the east of the Iberian Peninsula. All the markers studied present high genetic diversities, similar to those previously reported in other European population samples. No deviations from Hardy-Weinberg equilibrium were observed, with the exception of DXS101 locus. Allele frequencies and parameters of forensic interest for each X-STR were calculated. High mean exclusion chance and power of discrimination values were obtained by combining these 10 X-linked markers. Population comparisons (exact test of population differentiation; pairwise genetic distances) were carried out and low genetic distances were found between our sample and those from other Spanish or European regions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2007-12-01 | Forensic Science International |