6533b827fe1ef96bd1285d12

RESEARCH PRODUCT

IAPs and cell migration.

Laurence DubrezLaurence DubrezKrishnaraj Rajalingam

subject

MAPK/ERK pathwayCell signalingProgrammed cell deathInnate immune systemCell growthCellular differentiationCell migrationCell BiologyBiologyCell biologyInhibitor of Apoptosis Proteinsbody regionsApoptosisCell MovementCancer researchCell AdhesionAnimalsHumansCytoskeletonDevelopmental BiologySignal Transduction

description

Inhibitors of apoptosis (IAPs) constitute a family of cell signaling regulators controlling several fundamental biological processes such as innate immunity, inflammation, cell death, cell proliferation, and cell differentiation. Increasing evidence from in vivo and in vitro studies indicate a function for IAPs in the modulation of invasive and migratory properties of cells. Here, we present and discuss the mechanisms whereby IAPs can control cell migration.

yearjournalcountryeditionlanguage
2015-01-06Seminars in celldevelopmental biology
10.1016/j.semcdb.2015.02.015https://pubmed.ncbi.nlm.nih.gov/25769935