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RESEARCH PRODUCT
Ground and first excited electronic state interaction of FAD with some β-carboline derivatives
Rosa ValeroArmando CodoñerIsidro S. MonzóFrancisco Tomássubject
β carboline derivativesAqueous solutionExcited electronic statebiologyAbsorption spectroscopyChemistryGeneral EngineeringPhotochemistryFluorescenceCofactorStability constants of complexesbiology.proteinPhysical chemistryheterocyclic compoundsAbsorption (chemistry)description
Abstract The spectrophotometric and thermodynamic properties of molecular complexes of flavine adenine dinucleotide (FAD) with some dihydro β-carboline derivatives have been investigated in aqueous solution. The molecular associations have been examined by means of electronic absorption spectra, since in each a new charge-transfer band has been located, and also the variation of the fluorescence emission of FAD on the solutions has been observed. The formation constants for the molecular complexes were determined from absorption data, using the Foster-Hammick-Wardley method. The quenching fluorescence phenomena observed in FAD is related to the concentration of the dihydro β-carboline derivatives allowing the calculation of the association constants for FAD-β-carboline complexes. Thermodynamic parameters have been determined from the values of association constants for the molecular complexes at several temperatures.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1987-01-01 | Spectrochimica Acta Part A: Molecular Spectroscopy |