6533b827fe1ef96bd12866b9
RESEARCH PRODUCT
Analysis of DNA sequence variation within marine species using Beta-coalescents
Matthias SteinrückenMatthias BirknerJochen Blathsubject
Most recent common ancestorMutation ratePopulation geneticsInferenceMarine Biology62F99 (Primary) 62P10 92D10 92D20 (Secondary)Biology01 natural sciencesArticleDNA sequencingCoalescent theory010104 statistics & probability03 medical and health sciencesFOS: MathematicsAnimals0101 mathematicsQuantitative Biology - Populations and EvolutionEcology Evolution Behavior and Systematics030304 developmental biologycomputer.programming_languageMarine biology0303 health sciencesBETA (programming language)Probability (math.PR)Populations and Evolution (q-bio.PE)Sequence Analysis DNAOstreidaeEvolutionary biologyFOS: Biological sciencescomputerMathematics - Probabilitydescription
We apply recently developed inference methods based on general coalescent processes to DNA sequence data obtained from various marine species. Several of these species are believed to exhibit so-called shallow gene genealogies, potentially due to extreme reproductive behaviour, e.g. via Hedgecock's "reproduction sweepstakes". Besides the data analysis, in particular the inference of mutation rates and the estimation of the (real) time to the most recent common ancestor, we briefly address the question whether the genealogies might be adequately described by so-called Beta coalescents (as opposed to Kingman's coalescent), allowing multiple mergers of genealogies. The choice of the underlying coalescent model for the genealogy has drastic implications for the estimation of the above quantities, in particular the real-time embedding of the genealogy.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-08-01 |