6533b827fe1ef96bd1286775

RESEARCH PRODUCT

Safety assessment of food-contact paper and board using a battery of short-term toxicity tests: European union BIOSAFEPAPER project.

I. SeverinL. DahbiJ. -C. LhuguenotM. A. AnderssonD. HoornstraM. Salkinoja-salonenL. TurcoF. ZuccoA. StammatiO. DahlmanL. CastleM. SavolainenA. WeberU. Honkalampi-hamalainenA. Von Wright

subject

StandardizationHealth Toxicology and MutagenesisToxicologyMice0302 clinical medicineEnvironmental protectionShort term toxicityCells Culturedmedia_commonMammals0303 health sciencesFood PackagingRisk analysis (engineering)extraction proceduresChemistry (miscellaneous)030220 oncology & carcinogenesisSafetyPaperBattery (electricity)CellsFood Contamination[SDV.TOX.TCA]Life Sciences [q-bio]/Toxicology/Toxicology and food chainModels BiologicalRisk AssessmentGas Chromatography-Mass Spectrometry03 medical and health sciencesCell Line TumorToxicity TestsAnimalsHumansmedia_common.cataloged_instanceDimethyl Sulfoxidepaper and boardEuropean UnionEuropean union030304 developmental biologyEthanolFood contactMutagenicity Testsbusiness.industryPublic Health Environmental and Occupational HealthProduct testingWaterEnvironmental ExposureGeneral ChemistryConsumer protectionFood safetyCytotoxicity assaysBusinessFood AnalysisFood Science

description

International audience; An European Union (EU)-funded project QLK1-CT-2001-00930 (BIOSAFEPAPER) involves the development, validation and intercalibration of a short-term battery of toxicological tests for the safety assessment of food-contact paper and board. Dissemination of the results to industry, legislators (e.g. DG Consumer Protection, DG Enterprises, DG Research), standardization bodies such as CEN, and consumers will create an agreed risk evaluation procedure. The project involves pre-normative research in order to establish a set of in-vitro cytotoxicity and genotoxicity tests that will be easily adaptable to food-contact fibre-based materials and have endpoints relevant to consumer safety, including sub-lethal cellular events. These tests will be performed on samples representing actual migration conditions from food-contact paper and board with respect to different foodstuffs, and should form an experimental basis for scientifically sound recommendations for a harmonized system of risk evaluation and product testing.

http://www.cnr.it/prodotto/i/4617