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RESEARCH PRODUCT
Multinuclear magnetic resonance, electrospray ionization time-of-flight mass spectral and molecular modelling characterization of lithocholic acid amide esters with various nitrogen heterocycles
Jari TamminenElina VirtanenReijo KauppinenPia MänttäriMervi HaapalaErkki Kolehmainensubject
Lithocholic acidElectrospray ionizationchemistry.chemical_elementGeneral ChemistryCarbon-13 NMRNitrogenchemistry.chemical_compoundTime of flightPiperazinechemistryAmideProton NMROrganic chemistryGeneral Materials Sciencedescription
1H, 13C and 15N NMR and electrospray ionization time-of-flight mass spectrometric characterizations of five lithocholate esters of piperazine diamides are described. Two of them are cholaphane-type cyclic structures esterified with 2,2′-bipyridine-4,4 ′ - and pyridine-2,6-dicarboxylic acid and the other three esters are open structures comprising two or four lithocholyl residues. The conformational preferences of the dimeric congeners were examined by using molecular modelling and variable-temperature 1H NMR techniques. Copyright © 2003 John Wiley & Sons, Ltd.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2003-07-02 | Magnetic Resonance in Chemistry |