6533b827fe1ef96bd1286f48

RESEARCH PRODUCT

Recurrence of a laryngeal spindle cell sarcoma with a transformation into a higher grade of malignancy.

Torsten HansenKai FruthWolf J. MannD. KatenkampB.m. Lippert

subject

LarynxMalePathologymedicine.medical_specialtybusiness.industryMesenchymal stem cellSarcomaGeneral Medicinemedicine.diseaseMalignancystomatognathic diseasesmedicine.anatomical_structureFatal OutcomeOtorhinolaryngologyMedicineHumansSurgeryRadiotherapy AdjuvantSpindle cell sarcomaSarcomaNeoplasm Recurrence LocalbusinessClinical phenotypeLaryngeal NeoplasmsAged

description

Primary malignant mesenchymal neoplasms of the larynx are rare. Sarcomas of the larynx account for <1% of all malignant laryngeal mesenchymal neoplasms. This report examines a case of a recurring laryngeal, initial benign-appearing mesenchymal tumour, which first changed its clinical phenotype without any histological signs of malignancy and later also its histological appearance with signs of malignancy. Finally, it even underwent a transformation into a higher grade of malignancy. In addition to this, the difficulties of allocating this tumour to the correct sarcoma subentity are shown.

yearjournalcountryeditionlanguage
2009-08-01Auris, nasus, larynx
10.1016/j.anl.2008.10.009https://pubmed.ncbi.nlm.nih.gov/19121902