6533b827fe1ef96bd1287041

RESEARCH PRODUCT

Supportive und adjunktive Therapiemaßnahmen bei akutem Lungenversagen

Klaus MarkstallerMatthias David

subject

Mechanical ventilationmedicine.medical_specialtybusiness.industrymedicine.medical_treatmentGeneral MedicineOxygenationLung protective ventilationLung injuryCritical Care and Intensive Care MedicinePulmonary edemamedicine.diseaseNitric oxidelaw.inventionchemistry.chemical_compoundProne positionAnesthesiology and Pain MedicinechemistryRandomized controlled triallawEmergency MedicinemedicinebusinessIntensive care medicine

description

Various supportive and adjunctive therapies to conventional mechanical ventilation have been evaluated in patients with acute lung injury and acute respiratory distress syndrome (e.g. nitric oxide, prone position, surfactant, glucocorticoids). Although some investigations have shown promising improvements in oxygenation and physiological variables, large randomized trials of adjunctive and supportive therapies showed no impact on survival.

https://doi.org/10.1055/s-2008-1081394