6533b827fe1ef96bd1287108
RESEARCH PRODUCT
Identification of virulence factors and antibiotic resistance markers using bacterial genomics.
Didier RaoultJ. RathoredPierre-edouard FournierSofiane BakourPhilippe BiaginiS.a. Sankarsubject
0301 basic medicineMicrobiology (medical)medicine.medical_specialtyVirulence Factors[SDV]Life Sciences [q-bio]030106 microbiologyVirulenceComputational biologyBiologyMicrobiology03 medical and health sciencesAntibiotic resistanceDrug Resistance Multiple BacterialmedicineHumansWhole genome sequencingBacteriaVirulence[ SDV ] Life Sciences [q-bio]business.industryBacterial genomicsPublic healthHigh-Throughput Nucleotide SequencingGenomicsbiology.organism_classification3. Good healthBiotechnology[SDV] Life Sciences [q-bio]Infectious disease (medical specialty)Spectrometry Mass Matrix-Assisted Laser Desorption-IonizationbusinessGenome BacterialBacteriadescription
International audience; In recent years, the number of multidrug-resistant bacteria has increased rapidly and several epidemics were signaled in different regions of the world. Faced with this situation that presents a major global public health concern, the development and the use of new and rapid technologies is more than urgent. The use of the next-generation sequencing platforms by microbiologists and infectious disease specialists has allowed great progress in the medical field. Here, we review the usefulness of whole-genome sequencing for the detection of virulence and antibiotic resistance associated genes.
year | journal | country | edition | language |
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2016-02-29 |