6533b827fe1ef96bd1287175
RESEARCH PRODUCT
A Facile Synthesis of New 3-Substituted-2,3- dihydropyrido[3,2-d]pyrimidine-2,4-diones
Jamal LasriR. MamouniMohamed AkssiraElena Zaballos-garcíaA. ElhakmaouiM. Aadilsubject
chemistry.chemical_compoundchemistryPyrimidineOrganic ChemistryPyridineCondensationOrganic chemistryGeneral MedicineMedicinal chemistryIsocyanatedescription
Abstract Pyrido[3,2-d]pyrimidine-2,4-diones derivatives have been synthesized in good yields by two efficient synthetic routes, the first one through an hetero-cyclization on the ureas derivatives 3a–e under alkaline conditions, the second one by condensation of the isocyanate 2 with various arylalkylamines in pyridine.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2004-04-27 | Synthetic Communications |