0000000000620939

AUTHOR

M. Aadil

showing 2 related works from this author

A Facile Synthesis of New 3-Substituted-2,3- dihydropyrido[3,2-d]pyrimidine-2,4-diones

2004

Abstract Pyrido[3,2-d]pyrimidine-2,4-diones derivatives have been synthesized in good yields by two efficient synthetic routes, the first one through an hetero-cyclization on the ureas derivatives 3a–e under alkaline conditions, the second one by condensation of the isocyanate 2 with various arylalkylamines in pyridine.

chemistry.chemical_compoundchemistryPyrimidineOrganic ChemistryPyridineCondensationOrganic chemistryGeneral MedicineMedicinal chemistryIsocyanateSynthetic Communications
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Efficient synthesis of novel pyrido[3,2-d]pyrimidine-2,4-diones

2003

Abstract A series of pyrido[3,2- d ]pyrimidine-2,4-diones 5a – g have been synthesized through conversion of 2,3-pyridinedicarboxylic anhydride 1 into half-ester 2 , subsequent Curtius rearrangement and further reaction with amino acids.

chemistry.chemical_classificationchemistry.chemical_compoundPyrimidinechemistryStereochemistryOrganic ChemistryDrug DiscoveryOrganic chemistryGeneral MedicineBiochemistryCurtius rearrangementAmino acidTetrahedron Letters
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