0000000000620939
AUTHOR
M. Aadil
A Facile Synthesis of New 3-Substituted-2,3- dihydropyrido[3,2-d]pyrimidine-2,4-diones
Abstract Pyrido[3,2-d]pyrimidine-2,4-diones derivatives have been synthesized in good yields by two efficient synthetic routes, the first one through an hetero-cyclization on the ureas derivatives 3a–e under alkaline conditions, the second one by condensation of the isocyanate 2 with various arylalkylamines in pyridine.
Efficient synthesis of novel pyrido[3,2-d]pyrimidine-2,4-diones
Abstract A series of pyrido[3,2- d ]pyrimidine-2,4-diones 5a – g have been synthesized through conversion of 2,3-pyridinedicarboxylic anhydride 1 into half-ester 2 , subsequent Curtius rearrangement and further reaction with amino acids.