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RESEARCH PRODUCT
Efficient synthesis of novel pyrido[3,2-d]pyrimidine-2,4-diones
M. AadilJamal LasriR. MamouniJosé Sepúlveda-arquesMohamed Akssirasubject
chemistry.chemical_classificationchemistry.chemical_compoundPyrimidinechemistryStereochemistryOrganic ChemistryDrug DiscoveryOrganic chemistryGeneral MedicineBiochemistryCurtius rearrangementAmino aciddescription
Abstract A series of pyrido[3,2- d ]pyrimidine-2,4-diones 5a – g have been synthesized through conversion of 2,3-pyridinedicarboxylic anhydride 1 into half-ester 2 , subsequent Curtius rearrangement and further reaction with amino acids.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2003-07-01 | Tetrahedron Letters |