6533b827fe1ef96bd12871eb
RESEARCH PRODUCT
[Diagnostic performance of surface electrocardiogram in early detection of chagasic cardiomyopathy].
ÓScar Fabregat-andrésSalvador Morell-cabedoPilar García-gonzálezJordi Estornell-erillBruno Bochard-villanuevaFrancisco Ridocci-sorianosubject
Chagas diseaseAdultChagas CardiomyopathyMalemedicine.medical_specialtyCardiomyopathyEarly detectionAsymptomaticSensitivity and SpecificityElectrocardiographyCardiac magnetic resonance imagingInternal medicinemedicineHumanscardiovascular diseasesAsymptomatic InfectionsRetrospective Studiesmedicine.diagnostic_testbusiness.industryMagnetic resonance imagingMiddle Agedmedicine.diseaseMagnetic Resonance ImagingSurface electrocardiogramEarly Diagnosiscardiovascular systemCardiologyFemalemedicine.symptombusinessElectrocardiographydescription
Contrast-enhanced cardiac magnetic resonance imaging (CMR) allows early detection of myocardial involvement by Trypanosoma cruzi infection. The aim of our study was to assess the diagnostic performance of the surface electrocardiogram (ECG) in the early detection of Chagas' cardiomyopathy (CCM) compared with CMR.We included 43 asymptomatic patients (30 women, 42 ± 9.8 years), diagnosed of Chagas disease. The sample was divided into 2 groups according to the presence (n=17) or absence (n=26) of electrocardiographic abnormalities. All patients underwent CMR and late gadolinium enhancement (LGE) was used as a marker of early myocardial involvement.Six (14%) patients had a LGE significantly higher in the group who had electrocardiographic abnormalities (29 vs. 4%, P.05). With CMR as the method of reference, the ECG had a sensitivity of 83% and a negative predictive value of 96% to detect CCM.ECG is a useful, inexpensive and globally available tool for the screening of CCM in asymptomatic patients but with proven myocardial involvement in CMR.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-11-15 | Medicina clinica |