6533b828fe1ef96bd1287912
RESEARCH PRODUCT
Lipid and fatty acid variations inCiona intestinalis ovary after tri-n-butyltin(IV)chloride exposure
Tiziana FioreMaria Vittoria CangialosiPaolo D'agatiC. MansuetoEgidio PucciaLászló NagyConcetta Maria MessinaClaudia PelleritoMichelangelo ScopellitiLorenzo PelleritoValentina Mansuetosubject
Total lipidsCiona intestinaliChlorideFluiditytributyltinstresschemistry.chemical_compoundSettore BIO/10 - BiochimicaMembrane fluiditychemistry.chemical_classificationbiologymembrane fluidityarticlepolyunsaturated fatty acidBiological membranemedicine.anatomical_structureBiochemistrySettore CHIM/03 - Chimica Generale E InorganicaSynthesis (chemical)pollutantprostaglandintriacylglyceroladaptive behaviorPolyunsaturated fatty acidmedicine.drugSettore BIO/07 - EcologiaPhospholipidOvarylipid compositionSaccharomyces cerevisiaelong chain fatty acidOvarieInorganic ChemistrylipidmedicineCiona intestinalisdefense mechanismPolyunsaturated fatty acids (PUFA)TriglyceridesphospholipidnonhumanTriglycerideProstaglandineOvaryFatty acidGeneral ChemistryTBTClFatty acidbiology.organism_classificationprostaglandin synthesichemistryCelldescription
Reduction of total lipids (TL) content and significant variations of triglyceride (TG) and phospholipid (PL) fractions were observed as a consequence of exposure of Ciona intestinalis ovaries to tributyltin chloride (TBTCL) solutions. In particular, an evident TG decrease and a PL increase were observed, which probably provoked an increment in membrane fluidity, because of the high concentration of long chain fatty acids and, as a consequence, PL. This could be a cell adaptive standing mechanism towards the pollutants, as observed in Saccharomyces cerevisiae. Also the increase in the content of the polyunsaturated fatty acids (PUFA), important in the synthesis of compounds such as prostaglandine which are present in the ovary in a stress situation, was probably a consequence of a defense mechanism to the stress provoked by the presence of TBTCI. Copyright © 2005 John Wiley & Sons, Ltd.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2005-01-01 | Applied Organometallic Chemistry |