6533b828fe1ef96bd128798f

RESEARCH PRODUCT

A two-circuit apparatus for the perfusion of the isolated rat brain.

Josef KrieglsteinM. ReichmannW. Fleck

subject

PharmacologyEthanolbusiness.industryPharmacology toxicologyStopcockBrainElectroencephalographyGeneral MedicineIn Vitro TechniquesOxygenatorsRat brainRatsPerfusionMethodsMedicineAnimalsChlorineElectronicsbusinessPerfusionNeuroscience

description

A perfusion apparatus for the isolated rat brain is described which has two recirculating systems running synchronously. Instantaneous transfer from one circulating system to the other is possible by use of a 2-way stopcock, enabling different media to be perfused through the brain without interrupting the perfusion. The feasibility of the system is demonstrated experimentally.

10.1007/bf00500293https://pubmed.ncbi.nlm.nih.gov/4270073