6533b828fe1ef96bd1287a3b
RESEARCH PRODUCT
Clinical disorders responsible for plasma hyperviscosity and skin complications
Rosalia Lo PrestiMelania CarlisiGregorio CaimiE. HoppsCaterina Ursosubject
Pathologymedicine.medical_specialtyParaproteinemiasCryofibrinogenemiaHyperviscosityConnective tissuePlasma hyperviscosity030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicinehemic and lymphatic diseasesWhole-blood viscositySkin UlcerInternal MedicinemedicineHumansDysfibrinogenemiaConnective Tissue DiseasesMultiple myeloma030203 arthritis & rheumatologyintegumentary systembusiness.industryMicrocirculationDisease ManagementWaldenstrom macroglobulinemiaSyndromeBlood Viscositymedicine.diseaseCryoglobulinemiaDermatologymedicine.anatomical_structureCryoglobulinemiaWaldenstrom MacroglobulinemiaMultiple MyelomaComplicationbusinessdescription
In this brief review, we have examined some clinical disorders which are associated to an altered hemorheological profile and at times accompanied by skin ulcers. This skin condition may be, in fact, observed in patients with primary plasma hyperviscosity such as multiple myeloma, Waldenstrom macroglobulinemia, cryoglobulinemia, cryofibrinogenemia, dysfibrinogenemia and connective tissue diseases. It must be underlined that the altered hemorheological pattern is not the only responsible for this skin complication but, as it worsens the microcirculatory flow, it contributes to determine the occurrence of the skin ulcers.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-07-01 | European Journal of Internal Medicine |