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RESEARCH PRODUCT
Avoiding Pitfalls in the Interpretation of Gadoxetic Acid-Enhanced Magnetic Resonance Imaging
Marco Dioguardi BurgioValérie VilgrainValérie VilgrainLuisa PaulattoMaxime RonotMaxime RonotGiuseppe BrancatelliSylvain Terrazsubject
Gadolinium DTPAmedicine.medical_specialtyGadoxetic acidRadiology Nuclear Medicine and ImagingCirrhosisContrast Mediaddc:616.0757Sensitivity and Specificity030218 nuclear medicine & medical imagingMagnetic Resonance Imaging/methods03 medical and health sciences0302 clinical medicinePreoperative stagingGadolinium DTPAImage Interpretation Computer-AssistedmedicineHumansIn patientmedicine.diagnostic_testbusiness.industryLiver DiseasesLiver DiseaseImage Interpretation Computer-Assisted/methodsMagnetic resonance imagingDelayed phasemedicine.diseaseMr imagingMagnetic Resonance ImagingLiver Diseases/diagnostic imaging030211 gastroenterology & hepatologyRadiologyNuclear medicinebusinessmedicine.drugHumandescription
Gadoxetic acid is extensively used in the following 3 main clinical situations: characterization of small nodules in patients with cirrhosis, preoperative staging of liver metastases, and characterization of incidentally discovered focal liver lesions. Owing to the rapid entry of gadoxetic acid into hepatocytes, the traditional features of liver tumors are modified on magnetic resonance (MR) imaging, especially during delayed phase sequences. Thus, although the added value of gadoxetic acid for the detection and characterization of focal liver lesions is now clear, its unique pharmacokinetics as well as the presence of mimicking and atypical lesions may lead to misdiagnoses. The goal of this article is to illustrate common and uncommon pitfalls associated with the use of gadoxetic acid-enhanced MR imaging. Moreover, additional MR imaging features that can help establish a correct diagnosis are described.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-01-01 |