6533b828fe1ef96bd1288240
RESEARCH PRODUCT
Selective Synthesis of New Fluorinated Alicyclic β-Amino Ester Stereoisomers (Eur. J. Org. Chem. 26/2011)
Santos FusteroFerenc FülöpFerenc FülöpLoránd KissEnikő Forrósubject
Hydroxylationchemistry.chemical_classificationchemistry.chemical_compoundAlicyclic compoundChemistryOrganic ChemistryFluorinechemistry.chemical_elementOrganic chemistryPhysical and Theoretical Chemistrydescription
The cover picture shows a waterfall located in the Eastern Carpathians in Transylvania, near Bicaz Canyon. Although fluorinated organic compounds are nonexistent in nature, an increasing number of drugs (25 %) on the market contain at least one fluorine atom. Cyclic fluorinated β-amino acid derivatives have been synthesized by selective hydroxylation and hydroxy?fluorine exchange. Details are discussed in the article by F. Fulop et al. on p. 4993 ff.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-08-30 | European Journal of Organic Chemistry |