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RESEARCH PRODUCT
Appropriateness of percutaneous revascularization of coronary chronic total occlusions: an overview
Salvatore D. TomaselloMarouane BoukhrisMarouane BoukhrisEmmanouil S. BrilakisNicolaus ReifartCarlo Di MarioAlfredo R. GalassiBradley H. StraussMasahisa YamaneGerald S. WernerOsamu KatohStéphane RinfretGeorgios SianosDimitri Karmpaliotissubject
medicine.medical_specialtymedicine.medical_treatmentCoronary OcclusionTreatment OutcomeGuideline030204 cardiovascular system & hematologyRevascularizationlaw.invention03 medical and health sciencesPercutaneous Coronary Intervention0302 clinical medicineRandomized controlled trialQuality of lifelawCTO; PCIInternal medicinemedicineHumans030212 general & internal medicineIntensive care medicineCardiovascular outcome; Chronic total occlusion; Guidelines; PCI; Quality of life; Chronic Disease; Humans; Percutaneous Coronary Intervention; Quality of Life; Treatment Outcome; Coronary Occlusion; Cardiology and Cardiovascular Medicinebusiness.industryPercutaneous coronary interventionPCICardiovascular outcomeEvidence-based medicineCTOChronic total occlusionTreatment OutcomeCoronary OcclusionCoronary occlusionChronic DiseaseConventional PCIQuality of LifeCardiologyObservational studyCardiology and Cardiovascular MedicinebusinessHumandescription
Coronary chronic total occlusions (CTOs) are commonly encountered in patients undergoing coronary angiography. Several observational studies have demonstrated that successful CTO revascularization is associated with better cardiovascular outcomes and enhanced quality of life (QOL). However, in the absence of randomized trials, its prognostic benefit for patients remains debated. Over the past decade, the interest of the interventional community in CTO percutaneous coronary intervention (PCI) has exponentially grown due to important developments in dedicated equipment and techniques, resulting in high success and low complication rates. Both European and American guidelines have assigned a class IIa (level of evidence B) recommendation for CTO PCI. In the current review, we focus on the impact of CTO revascularization on clinical outcomes and QOL and on appropriate patient selection, and we provide a critical assessment of the current guidelines and recommendations on CTO PCI.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-01-01 | European Heart Journal |