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RESEARCH PRODUCT
Pigmented odontogenic keratocyst : report of a rare case and review of the literature
Celeste Sánchez-romeroCarla-isabelly Rodrigues-fernandesPaulo Rogério Ferreti BonanElaine Judite De Amorim CarvalhoOslei Paes De AlmeidaDanyel Elias Da Cruz Perezsubject
Pathologymedicine.medical_specialtyOral Medicine and Pathologybusiness.industryBlack maleCase Report:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseOdontogenicMelaninLesionOdontogenic cystRare caseUNESCO::CIENCIAS MÉDICASmedicineImmunohistochemistrysense organsKeratocystmedicine.symptombusinessGeneral Dentistrydescription
Pigmented odontogenic keratocyst (OKC) is very rare and its etiology remains uncertain. To the best of our knowledge, only 9 cases of pigmented OKC have been published in English-language literature. This report describes a pigmented OKC in a 14-year-old black male patient. Radiographically, the lesion appeared as a well-circumscribed, unilocular, and radiolucent image. A surgical excision was performed. Histopathological examination revealed an OKC. Additionally, a brownish, sparsed, intracytoplasmic pigmentation was observed in the basal cell layer, which was positive for Fontana-Masson staining. Immunohistochemistry reactions revealed positive dendritic cells for S-100 protein, HMB45 and Melan A. No clinical and imaging signs of recurrence were observed after 24 months. In conclusion, melanin apparently does not represent a factor for distinct biological behavior in OKC. Key words:Melanin, melanocytes, odontogenic cyst, odontogenic keratocyst, pigmented.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-12-01 |