6533b828fe1ef96bd1288f1e

RESEARCH PRODUCT

Conversion of crustacean hemocyanin to catecholoxidase

Heinz DeckerElmar Jaenicke

subject

Protein familyCopper proteinTyrosinasemedicine.medical_treatmentGeneral Physics and Astronomychemistry.chemical_elementchemical and pharmacologic phenomenacomplex mixturesOxygenStructural BiologyCrustaceamedicineAnimalsGeneral Materials ScienceCatechol oxidasechemistry.chemical_classificationbiologyActive sitehemic and immune systemsHemocyaninCell BiologyEnzymechemistryBiochemistryHemocyaninsbiology.proteinCatechol Oxidase

description

Crustacean hemocyanin as oxygen carrier and catecholoxidase as enzymes belong to the same protein family (type 3 copper proteins) sharing very similar active sites. Treatment with SDS of these hemocyanins results in an opening of the entrance to the active site for bulky phenolic compounds. This demonstrates, that almost all hemocyanin subunits possess the ability of catecholoxidase activity.

yearjournalcountryeditionlanguage
2004-03-24Micron
https://doi.org/10.1016/j.micron.2003.10.027