6533b828fe1ef96bd1288f2d

RESEARCH PRODUCT

CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination

Jan Frederik ScheelJan Frederik ScheelCarlos Sánchez-huertasVincenzo CostanzoIgnasi RoigUwe WolfrumTravis H. StrackerBerta TerréPeter J. MckinnonPhilip A. KnobelSuvi AivioSarai PachecoMarko MarjanovićLluís PalenzuelaJens LüdersAna Martínez-marchalJosé A. SujaRocío Gómez

subject

MaleProgrammed cell deathMicrocephalyGeneral Physics and AstronomyCell Cycle ProteinsDwarfismBiologyReal-Time Polymerase Chain ReactionArticleGeneral Biochemistry Genetics and Molecular BiologyMice03 medical and health sciences0302 clinical medicineChromosome structureSpermatocytesmedicineAnimalscentrioleHomologous Recombination030304 developmental biologyRecombination GeneticfertilityGeneticsCentrosomeMeiotic recombination0303 health sciencesMultidisciplinarySperm CountProtein cep63FaciesGeneral Chemistrymedicine.diseaseBiología y Biomedicina / BiologíaImmunohistochemistryNeural stem cell3. Good healthCEP63MeiosisSeckel syndromeCentrosomeMicrocephalyTumor Suppressor Protein p53Homologous recombinationmicrocephaly ; DNA damage ; centrosome ; meiosis030217 neurology & neurosurgeryDNA Damage

description

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAM

10.1038/ncomms8676http://hdl.handle.net/10486/675309