6533b828fe1ef96bd1288f49
RESEARCH PRODUCT
PARAMETER BOUNDED ESTIMATION FOR QUASISPECIES MODELS OF MOLECULAR EVOLUTION
Laura GiarreP. Falugisubject
Set (abstract data type)education.field_of_studyMathematical optimizationIdentification (information)Molecular evolutionBounded functionPopulationReplication (statistics)Viral quasispeciesBiologyeducationEvolutionary dynamicsdescription
Abstract The Quasispecies models identification for Evolutionary Dynamics is considered in a worst-case deterministic setting. These models analyze the DNA and RNA evolution or describe the population dynamics of viruses and bacteria. In this paper we identify the Fitness and the Replication Probability parameters of a genetic sequences, subject to a set of stringent constraints to have physical meaning and to guarantee positiveness. The conditional central estimate and the Uncertainty Intervals are determined. The effectiveness of the proposed procedure has been illustrated by means of simulation experiments while tests on real data are under concern.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-01-01 | IFAC Proceedings Volumes |