6533b829fe1ef96bd12896ac

RESEARCH PRODUCT

ChemInform Abstract: Thioetherification of Chloroheteroarenes: A Binuclear Catalyst Promotes Wide Scope and High Functional-Group Tolerance.

Novi WijayaMélanie PlatonMark SaeysJean-cyrille HiersoJean-cyrille HiersoYoann RousselinVincent RampazziLuchao Cui

subject

chemistry.chemical_compoundScope (project management)LigandChemistryFunctional groupNucleophilic substitutionGeneral MedicineCombinatorial chemistryCatalysis

description

The nucleophilic substitution of a variety of chloro- and bromohetarenes with arylthiols is optimized to use [PdCl(allyl)]2 in combination with a ferrocenyltetraphosphane as ligand.

https://doi.org/10.1002/chin.201512124