6533b829fe1ef96bd1289916

RESEARCH PRODUCT

ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part I: Epidemiology, assessment of extrapulmonary conditions, candidate evaluation, selection criteria, and pathology statements

Gerald J. BerryDaniel F. DillingSofya TokmanAida VenadoHeather M. StrahTanya McwilliamsVaidehi KazaBrad BemissMarie BudevArun NairKatharina WassilewSangeeta BhoradeRupal J. ShahHilary J. GoldbergM. HowsareErika D. LeaseMichelle MurrayAmparo SoléCynthia J. GriesKeith C. MeyerJuan C SalgadoCarol FarverCaroline M. PattersonAre Martin HolmNora SandorfiMaria M. CrespoKeith WillieJérôme Le PavecJosé M. CifriánLaurie D. SnyderOsnat Shtraichman

subject

Pulmonary and Respiratory Medicinemedicine.medical_specialtyConsensusmedicine.medical_treatmentDiseaseGlobal HealthEpidemiologyHumansMedicineLung transplantationConnective Tissue DiseasesIntensive care medicineSelection (genetic algorithm)TransplantationLungbusiness.industryContraindicationsPatient Selectionmedicine.diseaseConnective tissue diseaseTransplantationmedicine.anatomical_structureSurgeryCTDMorbidityCardiology and Cardiovascular MedicinebusinessLung Transplantation

description

Patients with connective tissue disease (CTD) and advanced lung disease are often considered suboptimal candidates for lung transplantation (LTx) due to their underlying medical complexity and potential surgical risk. There is substantial variability across LTx centers regarding the evaluation and listing of these patients. The International Society for Heart and Lung Transplantation-supported consensus document on lung transplantation in patients with CTD standardization aims to clarify definitions of each disease state included under the term CTD, to describe the extrapulmonary manifestations of each disease requiring consideration before transplantation, and to outline the absolute contraindications to transplantation allowing risk stratification during the evaluation and selection of candidates for LTx.

https://doi.org/10.1016/j.healun.2021.07.014