6533b829fe1ef96bd1289b26

RESEARCH PRODUCT

Effect of pinealectomy and circadian rhythm on avoidance behavior in the male rat.

A. RomanJ.m. Viña GinerF. PallardoP. VillanuevaM.d. Catalá

subject

Malemedicine.medical_specialtySh groupsBrain Mappinggenetic structuresLightPeriod (gene)medicine.medical_treatmentPinealectomyExperimental and Cognitive PsychologyBiologyPineal GlandCircadian RhythmRatsBehavioral NeuroscienceEndocrinologyInternal medicineMale ratsmedicineAvoidance LearningExploratory BehaviorAnimalsDaylightCircadian rhythm

description

Male adult albino rats were divided into six groups: two pinealectomized (Px); two sham-operated (Sh) and two serving as controls (C). Half of these groups were studied in daylight and the other half at night. The animals were open-field tested and then conditioned by the avoidance behavior test in the appropriate light period. No differences were observed among the groups when they were conditioned in the dark; however, the Px were conditioned significantly more rapidly than Sh or C in daylight. Intragroup comparisons between night/day conditioning showed them to be similar in Px but more rapid at night in both Sh and C. The Sh group is unique and not comparable to controls.

10.1016/0031-9384(85)90191-xhttps://pubmed.ncbi.nlm.nih.gov/4011714