6533b829fe1ef96bd1289b79
RESEARCH PRODUCT
Causal cross-spectral analysis of heart rate and blood pressure variability for describing the impairment of the cardiovascular control in neurally mediated syncope
Renzo AntoliniM. Del GrecoLuca FaesGiandomenico NolloL. Widesottsubject
AdultMalemedicine.medical_specialtyStatistics as TopicBiomedical EngineeringBlood PressureNeurally-mediated syncopeCardiovascular controlBaroreflexCardiovascular SystemSensitivity and SpecificitySeverity of Illness IndexFeedbackElectrocardiographyHeart RateInternal medicineSeverity of illnessHeart rateSyncope VasovagalmedicineHumansComputer SimulationDiagnosis Computer-AssistedModels Statisticalmedicine.diagnostic_testbusiness.industryTransfer functionModels CardiovascularReproducibility of ResultsBaroreflexBlood pressureData Interpretation StatisticalAnesthesiaCardiologyRegression AnalysisFemalebusinessElectrocardiographyCoherenceAlgorithmsSyncope (phonology)description
A causal approach to the calculation of coherence and transfer function between systolic pressure (SP) and RR interval variability was applied in eight patients and eight control subjects during prolonged tilt test for investigating the impairment of cardiovascular control related to neurally mediated syncope. The causal analysis showed a depressed baroreflex regulation in resting patients, with reduced gain and increased latency from SP to RR, and a drop of the baroreflex coupling immediately before syncope. These findings, which were not elicited by traditional cross-spectral analysis, strongly suggest the use of the causal approach for the study of syncope mechanisms. © 2006 IEEE.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-01-13 |