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RESEARCH PRODUCT
Population structure in the Méditerranean basin: a Y chromosome perspective
Alex E. FeliceAndrea NovellettoA. BerebbiVincenzo Lorenzo PascaliValérie DelagueAndré MégarbanéDavid GoldsteinPavlos NeophytouNicola RedheadGérard LefrancPatrizia MalaspinaMarc FellousL. TerrenatoMark G. ThomasValentino RomanoCristian CapelliCristian CapelliZ. PoulliFilippo Calisubject
Mediterranean climateMaledemographyhaplotypeSouthern EuropegenotypeUEPsPopulation geneticsVariation (Genetics)ArabMediterraneanMediterranean BasinArab; article; cluster analysis; demography; gene locus; genetic linkage; genetic variability; genotype; haplotype; human; male; North Africa; population genetics; population structure; priority journal; Southern Europe; Y chromosome Chromosomes Human Y; Ethnic Groups; Genetics Population; Humans; Male; Mediterranean Region; Variation (Genetics)genetic linkagegenetic variabilityEthnicity[SDV.BDD]Life Sciences [q-bio]/Development BiologyGenetics (clinical)Genetics0303 health scienceseducation.field_of_studyEcologyMediterranean Region030305 genetics & heredityarticlepriority journalMediterranean; Population genetic structure; STRs; UEPs; Y chromosomeY-chromosome population genetics ArabYgene locusPopulationPopulationEthnic GroupsBiologyY chromosomeChromosomes03 medical and health sciencesGenetic variationGeneticsHumansPopulation genetic structureGenetic variabilityhumaneducation030304 developmental biology[SDV.GEN]Life Sciences [q-bio]/GeneticsChromosomes Human YY chromosomeHaplotypeGenetic Variationpopulation geneticspopulation structureSettore MED/43 - MEDICINA LEGALENorth AfricaSettore BIO/18 - GeneticaGenetics PopulationSTRscluster analysisdescription
The Mediterranean region has been characterised by a number of pre-historical and historical demographic events whose legacy on the current genetic landscape is still a matter of debate. In order to investigate the degree of population structure across the Mediterranean, we have investigated Y chromosome variation in a large dataset of Mediterranean populations, 11 of which are first described here. Our analyses identify four main clusters in the Mediterranean that can be labelled as North Africa, Arab, Central-East and West Mediterranean. In particular, Near Eastern samples tend to separate according to the presence of Arab Y chromosome lineages, suggesting that the Arab expansion played a major role in shaping the current genetic structuring within the Fertile Crescent.
year | journal | country | edition | language |
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2006-03-01 |