6533b829fe1ef96bd128a46e

RESEARCH PRODUCT

Non-toxic cyanide sources and cyanating agents

Alexander M. NauthTill Opatz

subject

Nitrile010405 organic chemistryCyanideOrganic ChemistryCyanation010402 general chemistry01 natural sciencesBiochemistryCombinatorial chemistry0104 chemical scienceschemistry.chemical_compoundchemistryNucleophileElectrophilePhysical and Theoretical Chemistry

description

The present review gives an overview over non-toxic cyanation agents and cyanide sources used in the synthesis of structurally diverse products containing the nitrile function. Nucleophilic as well as electrophilic agents/systems that transfer the entire CN-group were taken in consideration. Reactions in which a preexisting carbon functionality is transformed into a nitrile function by addition of nitrogen are however not covered here.

https://doi.org/10.1039/c8ob02140f