6533b829fe1ef96bd128ad2e
RESEARCH PRODUCT
Ascorbic Acid in Postoperative Intensive Care Patients - Biochemical Aspects and Clinical Experience
Andreas Rümelinsubject
medicine.medical_specialtyAntioxidantmedicine.medical_treatmentAscorbic AcidBiochemistryGastroenterologyAntioxidantslaw.inventionHypovitaminosislawInternal medicineIntensive careDrug DiscoveryHumansMedicinePostoperative CarePharmacologybusiness.industryOrganic ChemistryAscorbic acidIntensive care unitSurgeryParenteral nutritionWounds and InjuriesMolecular Medicinebusinessdescription
The transport mechanisms of ascorbic acid (AA) are described. The metabolism of AA and its function as an antioxidant are covered in some detail. Subsequently, indications for postoperative substitution are discussed. The supplementation of up to 300 mg of AA per day in postoperative intensive care unit patients during par-/enteral nutrition is recommended to prevent hypovitaminosis. It is not clear if this is the optimal dosage of AA in postoperative/-trauma patients. New aspects for an AA substitution are discussed.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2009-01-20 | Current Medicinal Chemistry |