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RESEARCH PRODUCT
The Influence of Oxidative Stress on Neurological Outcomes in Spontaneous Intracerebral Hemorrhage
Harald KrenzlinJohannes LotzThomas KerzNaureen KericChristina FrenzJan SchmittFlorian RingelJochem KönigElena KurzJulia Masomi-bornwasserDominik M. A. Wespsubject
Adultmedicine.medical_specialtyInflammationmedicine.disease_causeBiochemistryGastroenterologyMicrobiologyArticlecerebrospinal fluidSuperoxide dismutasechemistry.chemical_compoundCerebrospinal fluidInternal medicineMalondialdehydemedicineHumansoxidative stresscardiovascular diseasesMolecular Biologyneurological outcomeCerebral Hemorrhagechemistry.chemical_classificationIntracerebral hemorrhageGlutathione Peroxidasebiologybusiness.industryGlutathione peroxidaseGlutathioneMiddle AgedMalondialdehydemedicine.diseaseintracerebral hemorrhageQR1-502nervous system diseaseschemistrybiology.proteinmedicine.symptombusinessOxidative stressoxidative stress markersdescription
Spontaneous intracerebral hemorrhage (ICH) causes, besides the primary brain injury, a secondary brain injury (SBI), which is induced, amongst other things, by oxidative stress (OS) and inflammation, determining the patient’s outcome. This study aims to assess the impact of OS in plasma and cerebrospinal fluid (CSF) on clinical outcomes in patients with ICH. A total of 19 ICH (volume >
year | journal | country | edition | language |
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2021-11-01 | Biomolecules |