Adenīna limitācijas ietekme uz maizes rauga Saccharomyces cerevisiae šūnu fizioloģiju un morfoloģiju

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Adenīna limitācijas ietekme uz maizes rauga Saccharomyces cerevisiae šūnu fizioloģiju un morfoloģiju

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Audzējot barotnē ar ierobežotu adenīna daudzumu adenīna auksotrofu un prototrofu maizes rauga celmu, tika izpētīta adenīna limitācijas ietekme uz rauga šūnu morfoloģiskajiem parametriem. Tika novērots, ka pēc adenīna izsīkšanas barotnē auksotrofās šūnas pārstāj augt, taču turpinās kultūras optiskā blīvuma un sausā svara pieaugums. Reizē ar adenīna limitācijas iestāšanos šūnas sāk pastiprināti uzkrāt trehalozi, kā arī pieaug to izmēri. Salīdzinot šūnu izdzīvotību adenīna, leicīna un slāpekļa iztrūkuma apstākļos, atklājās, ka adenīna badinātas šūnas spēj efektīvāk arestēt šūnas ciklu G1/G0 fāzē un saglabāt ievērojami augstāku dzīvotspēju nekā leicīna badinātas šūnas. Adenīna limitācijā tika novērota arī glikozes izšķiešana. Iegūtie dati liecina, ka adenīna limitācijas fizioloģiskie procesi ir atšķirīgi no citām auksotrofajām limitācijām.

year	journal	country	edition	language
2013-01-01

https://dspace.lu.lv/dspace/handle/7/15878

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