6533b82afe1ef96bd128b8e9
RESEARCH PRODUCT
Antigen-specific T cells and cytokines detection as useful tool for understanding immunity against zoonotic infections.
Guido SireciAlessandra TorinaSanto CaracappaFabrizio VitaleMarco Pio La MannaFrancesco DieliAnnalisa AgnoneS. VillariG. Vescosubject
lcsh:Immunologic diseases. AllergyNematodaT-LymphocytesImmunologyReview ArticleAdaptive ImmunityBiologyHost-Parasite InteractionsImmune systemT-Lymphocyte SubsetsAntigen specificImmunityZoonosesAnimalsHumansImmunology and AllergyAntigensTh1-Th2 BalanceZoonoses antigen specific T-cells animal immunology.VaccinesBacteriaZoonotic InfectionGeneral MedicineAcquired immune systemVirologyImmunity InnateHost-Pathogen InteractionsImmunologyCytokinesAdaptationlcsh:RC581-607description
Zoonoses include a broad range of diseases, that are becoming of great interest, due to the climate changing, that cause the adaptation of vectors to new niches and environments. Host immune responses play a crucial role in determining the outcome of infections, as documented by expansion of antigen-specific T cells during several zoonotic infections. Thus, understanding of the contribution of antigen-specific T-cell subsets in the host immune response is a powerful tool to evaluate the different immunological mechanisms involved in zoonotic infections and for the development of effective vaccines. In this paper we discuss the role of T cells in some eukaryotic and prokaryotic infectious models.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-02-01 |