6533b82afe1ef96bd128c016

RESEARCH PRODUCT

Long-Term Potentiation in Slices from Human Hippocampus

B. HeimrichHelmut L. HaasR. W. GreeneX. Xie

subject

Synaptic potentialnervous systemChemistrySynaptic plasticityHippocampus (mythology)Long-term potentiationPopulation spikeHippocampal formationNeuroscienceIntracellularIn vitro

description

Long-term potentiation (LTP) has been observed in slices from human hippocampi removed for intractable epilepsy using extra- and intracellular recording in vitro. Furthermore the effects of several neuroactive substances with possible relevance for synaptic plasticity was investigated. Human hippocampal neurones in vitro display properties very similar to the respective rodent cells.

yearjournalcountryeditionlanguage
1988-01-01
https://doi.org/10.1007/978-3-642-73202-7_23