6533b82afe1ef96bd128c029

RESEARCH PRODUCT

Strategies for Making Life

Manuel PorcarJuli Peretó

subject

TransplantationProtocellSynthetic biologyXenobiologyArtificial cellComputer scienceArtificial lifeMetabolic networkData science

description

Synthetic biology is a multifaceted discipline and the pathways towards an artificial cell are diverse. Top-down strategies seek simplification of genomes, their chemical synthesis and transplantation into a cell chassis. In the long term, scientists hope to have genomic platforms to reinvent metabolic networks capable of producing molecules of biotechnological interest. On the other hand, a bottom-up strategy relies on the chemical implementation of fundamental concepts such as self-reproduction, self-replication and self-maintaining systems. In addition to the artificial synthesis of simplified genomes and protocells, some scientists explore xenobiology, or making life as we do not know it, for example, with different genetic alphabets or with artificially designed metabolic pathways.

https://doi.org/10.1007/978-94-017-9382-7_4