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RESEARCH PRODUCT

Impact of Ceramic and Metallic Nano-scaled Particles on Endothelial Cell Functionsin vitro

Andrea GambarelliC. James KirkpatrickRonald E. UngerAntonietta GattiKirsten PetersEnrico Sabbioni

subject

Endothelial stem cellMaterials scienceTransmission electron microscopyCell culturemedia_common.quotation_subjectNanoparticleParticleInternalizationCytotoxicityIn vitroCell biologymedia_common

description

The sections in this article are Introduction Origin of Particles in the Human Environment Evidence for Size-dependent Toxicity of Particles Dissemination and Interferences of Nanoparticles within the Body Endothelial Cells and Nanoparticle Exposure Testing of Nanoparticle-induced Effects on Human Endothelial Cells In Vitro Materials and Methods Cell Culture Particles Transmission Electron Microscopy (TEM) Cytotoxicity Assay Detection of Ki67 Expression Quantification of IL-8 Release in Cell Culture Supernatant Quantification of E-selectin Cell Surface Protein Expression Fluorescence Staining Statistical Analysis Results Discussion Particle Internalization Particle Cytotoxicity Pro-inflammatory Activation Conclusions and Consideration of the Risk of Nanoparticles to Human Health Acknowledgments

https://doi.org/10.1002/9783527610419.ntls0052