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RESEARCH PRODUCT
Harmful and Protective Effects of Phenolic Compounds from African Medicinal Plants
Victor KueteQiaoli ZhaoArmelle T. Mbavengsubject
NaringeninTraditional medicinefood and beveragesCatechinPlumbaginEpigallocatechin gallateBiologychemistry.chemical_compoundchemistryScopoletinBotanyheterocyclic compoundsMedicinal plantsKaempferolQuercetindescription
Phenolic phytochemicals include flavonoids, phenolic acids, tannins, lignans, coumarins, quinones, xanthones, cucurmin, and several other plant compounds owing hydroxyl group bonded directly to an aromatic hydrocarbon group. In plants, they play a variety of protective effects against abiotic stresses like UV light or biotic stresses such as predator and pathogen attacks. This role is exploited by humans to treat several ailments including bacterial, fungal, protozoal and viral infections, inflammation, cancer, and diabetes. Numbers of them are known to display direct protection on cells or organs in humans and animals. In contrast, some of others rather have harmful or toxic effects. In this chapter, the synopsis of both protective and harmful effects of phenolics identified in African plants is provided. Emphasis is made on the potential toxic effects of chamuvaritin, gossypol, plumbagin, and scopoletin and the protective roles of catechin, epigallocatechin gallate, genistein, kaempferol, morin, naringenin, quercetin, resveratrol, and rutin.
year | journal | country | edition | language |
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2014-01-01 |