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RESEARCH PRODUCT

O069. Menstrual cycle affects cortical excitability differently in females with migraine and in healthy controls: a new perspective by cross modal sound induced flash illusions

Simona MaccoraGiuseppe VallarBrigida FierroFilippo BrighinaPiera PaladinoRoberta BaschiGiuseppe CosentinoCarlo ManninaNadia Bolognini

subject

medicine.medical_specialtyNeurologygenetic structuresmedia_common.quotation_subjectIllusionClinical NeurologyM-PSI/02 - PSICOBIOLOGIA E PSICOLOGIA FISIOLOGICAMigraine Progesterone Estradiol Menstrual Cycle Visual Cortexmenstrual migrainePerceptionmedicineMenstrual cyclemedia_commonbusiness.industryPerspective (graphical)General Medicinecortical excitabilitymedicine.diseasesound induced flash illusionsVisual cortexmedicine.anatomical_structureAnesthesiology and Pain MedicineMigrainemenstrual migraine; cortical excitability; sound induced flash illusionsOral PresentationSettore MED/26 - Neurologiasense organsNeurology (clinical)businessNeuroscienceHormone

description

The sound-induced flash illusions (SIFI) represent a valid tool to explore multimodal perception and are critically dependent on visual and acoustic cortical excitability [1, 2]. In a previous study [3], we observed a significant reduction of illusions in migraine patients with respect to healthy controls, probably due to a condition of visual cortex hyperexcitability. Aim of the present study was to evaluate SIFI perceptions in healthy women and patients with menstrual migraine and to describe the effects of cyclical change of steroid hormones and cortical responsiveness.

10.1186/1129-2377-16-s1-a141http://dx.doi.org/10.1186/1129-2377-16-s1-a141