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RESEARCH PRODUCT
Coronary artery stenosis treatment in aging patients with inherited Factor VII deficiency: Where do we stand?
Mariasanta NapolitanoSergio Siragusasubject
AdultMalemedicine.medical_specialtyFactor VII DeficiencyCardiovascular risk factorsCoronary stenosis030204 cardiovascular system & hematology03 medical and health scienceschemistry.chemical_compoundAntithrombotic treatment0302 clinical medicineInternal medicinemedicineHumanscardiovascular diseasesFactor VII deficiencyChildAgedFactor VIIbusiness.industryCoronary StenosisHematologyMiddle Agedmedicine.diseaseThrombosischemistryCardiologyFemalebusiness030215 immunologydescription
Aging with rare bleeding disorders such as factor VII (FVII) deficiency poses several challenges to treatment because of the occurrence of cerebral and cardiovascular age-related comorbidities and high bleeding risks. We report a case of long-term treatment with antiplatelet agents and contemporary prophylaxis of bleeding in a woman affected by severe FVII deficiency diagnosed with symptomatic coronary artery stenosis. Information on the management of antithrombotic treatment in rare bleeding disorders is lacking and mainly limited to anecdotal reports or side effects secondary to replacement therapy. We also briefly reviewed available data on the treatment of arterial thrombosis in FVII deficiency.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-12-01 | Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis |