6533b82afe1ef96bd128ca82

RESEARCH PRODUCT

Room-temperature ionic liquid-based electrochemical nanobiosensors

Miguel De La GuardiaMohammad HasanzadehNasrin ShadjouMorteza Eskandani

subject

chemistry.chemical_compoundMaterials sciencechemistryIonic liquidElectrodeElectrochemical biosensorNanotechnologyElectrochemistryBiosensorSpectroscopyAnalytical Chemistry

description

Abstract Room-temperature ionic liquids (RTILs) have proved to be excellent materials for applications in electrochemistry. We review progress in constructing high-performance electrochemical biosensors. We also discuss: • different modified electrodes based on RTILs for biosensing applications; • different routes for enzyme biosensing based on RTIL-modified electrodes; • incorporation of biorecognition elements into RTIL-based electrodes; • electroanalytical applications of RTIL-based modified electrodes; and, • recent developments in which the advantages of ILs as a medium for biosensing were realized. We also summarize the latest developments in the applications of RTIL-based electrochemical biosensors in ultrasensitive detection of biological entities, especially nucleic acids and proteins. We review different types of RTIL-based electrochemical biosensors (e.g., based on enzymes, proteins and nucleic acids) in terms of their sensing performance and potential for future development.

yearjournalcountryeditionlanguage
2012-12-01TrAC Trends in Analytical Chemistry
https://doi.org/10.1016/j.trac.2012.09.005